MDCT Evaluation of Hepatic Manifestations in Malignant Hematological Disorders

Author Info

Adel El-Badrawy Ahmed Tawfik Gehad Saleh Mai Abdel-Naby Hayam Ghazy Ziad Emarah Ahmed Ramez Mohamed A. Elfatah Ahmed Eltantawy Mona M. Taalab Noha Eisa Shaimaa El-Ashwah Yasmine Essam Basma Atef Shahira Ali El-Etreby Monir H. Bahgat Ahmed Deiab Hatem Elalfy Tarek Besheer Ahmed El-Mesery Mohamed Mahmoud Sarhan Suzy Abd Elmabood Ahmed Megahed Mohamed Farouk Akl Khaled Abouelkhair Hanan Wahba Amal Halim Nirmeen Megahed Eman Omar Khashaba

Corresponding Author

Adel El-Badrawy
Radiology Department, Mansoura Faculty of Medicine, Mansoura University, Egypt

A B S T R A C T

Objective: The aim of this work was to evaluate Multidetector Computed Tomography (MDCT) findings of hepatic manifestation in common malignant hematological disorders. Materials and Methods: This retrospective study included 300 patients with different types of malignant hematological disorders. They were 119 female and 181 male (mean age, 45.4 year; range, 5-70 years). The most common hematological disorder was Non-Hodgkin lymphoma (NHL) detected in 192/300 (64%) patients and then Hodgkin disease (HD) detected in 40/300 (13.3%) patients. All 300 patients had ultrasonography. Clinical evaluation and laboratory assessment were done for all patients. Whole body and triphasic abdominal CT scanning was performed on 64 MDCT systems. Results: MDCT scanning revealed hepatic affection in 82/192 of NHL. All these 82 cases revealed hepatomegaly and focal lesion detected in 36 cases. As regard Hodgkin disease (HD), hepatomegaly detected in 22/40 cases and focal lesion detected in 8/40 cases. Hepatomegaly detected in 8/14 cases of acute myeloid leukemia (AML) and focal lesion detected in 4/14 cases. In cases of chronic lymphocytic leukemia (CLL), hepatomegaly detected in 6/22 cases with no detection of focal lesion. Conclusion: Hepatic involvement is often observed in several malignant hematological disorders, resulting in abnormalities in liver imaging studies. Malignant hematological disorders must be considered in hepatomegaly and hepatic focal lesions either single or multiple. MDCT is the diagnostic modality of choice for diagnosis and follow up of liver affection in different malignant hematological disorders.

Article Info

Article Type

Research Article

Publication history

Received: Thu 29, Oct 2020
Accepted: Mon 09, Nov 2020
Published: Thu 19, Nov 2020

Copyright

© 2023 Adel El-Badrawy. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Hosting by Science Repository.
DOI: 10.31487/j.CDM.2020.02.01