Successful Pregnancy in Infertile Elderly Woman with Polycystic Ovarian Syndrome after Multiple Attempts of Ovarian Stimulation: A Case Report

Author Info

Shuichi Iida

Corresponding Author

Shuichi Iida
Department of Gynecology, Pref. Museum IVF Clinic, Suruga Ward Shizuoka City Shizuoka Prefecture, Japan

A B S T R A C T

Ovarian stimulation (OS) in infertile elderly women with polycystic ovary syndrome (PCOS) is challenging because of the high risk of ovarian hyperstimulation syndrome (OHSS) and the possibility of age-related poor response. We present a case of an elderly woman with anovulation due to PCOS who achieved pregnancy in the sixth intrauterine insemination (IUI) combined with letrozole plus gonadotropin without any adverse effects since OS using the clomiphene citrate (CC) or gonadotropin was not effective. In the clinical course of this case, adequate follicular development was not achieved by OS using CC only, and severe OHSS arose using FSH only. The regular and adequate follicular development by using OS combined with letrozole plus gonadotropin could be conceived by repeated IUI. The OS method combined with letrozole plus gonadotropin was effective for elderly women with anovulation due to PCOS.

Article Info

Article Type

Case Report

Publication history

Received: Thu 13, Jun 2024
Accepted: Wed 17, Jul 2024
Published: Mon 19, Aug 2024

Copyright

© 2023 Shuichi Iida. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Hosting by Science Repository.
DOI: 10.31487/j.CROGR.2024.01.01