Novel Composite Nanocarriers

Author Info

Ignác Capek

Corresponding Author

Ignác Capek
Slovak Academy of Sciences, Institute of Measurement Science, Bratislava, Slovakia

A B S T R A C T

Need for materials with high biocompatible properties have led to the development of prodrug-decorated nanoparticles. The structure of present nanostructures consists of the hydrophobic core and hydrophilic shell. The shell acts as an external envelop which enhances the colloidal stability of dispersion which protects the prodrug of the nanoparticles from photo- and thermal-initiated degradation. The composite nanoparticles coated by organic shells with functional groups were considered to govern the covalent immobilization of therapeutics/biomolecules. The nanoparticles with unique physiochemical properties may be useful as biosensors in living whole cells. The enhanced cellular drug delivery to cancer cell lines via nanoconjugates revealed that smart nanoparticles are an effective tool for transporting and delivering drugs.

Article Info

Article Type

Review Article

Publication history

Received: Thu 02, Jan 2020
Accepted: Wed 22, Jan 2020
Published: Thu 30, Jan 2020

Copyright

© 2023 Ignác Capek. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Hosting by Science Repository.
DOI: 10.31487/j.GDT.2020.01.02