Purely Intraparenchymal Plasmacytoma: A Diagnostic Conundrum. To Operate or Radiate?

Author Info

Andrew  J. Kobets Emad Eskandar James Goodrich Patrick Lasala Rose Fluss Vijay Agarwal

Corresponding Author

Andrew  J. Kobets
Department of Neurological Surgery, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, New York

A B S T R A C T

Intracranial plasmacytomas are rare entities that are thought to spread to the intraparenchymal space via pre-existing lesions from the dura or skull. Purely intraparenchymal plasmacytomas, without cranial or dural involvement, are therefore, rarer and seem to contradict the mechanism of spread that have been attributed to these lesions. Only a few cases of purely intraparenchymal lesions have been described in the literature, and they represent diagnostic conundrums when identified as they mimic the radiographic appearance of other parenchymal lesions, such as metastatic tumors or infectious collections. The authors report an unusual case of a purely intraparenchymal plasmacytoma in the right frontal lobe of a 68-year-old female with a known history of multiple myeloma. No evidence of extension from a cranial or dural-based lesion was found radiographically or intraoperatively and given the non-diagnostic radiographic features of this plasmacytoma, the diagnosis was made upon pathological examination after gross total resection. A review of the literature on purely intraparenchymal plasmacytomas is provided and the management and prognosis of these lesions are addressed.

Article Info

Article Type

Case Report

Publication history

Received: Sat 04, May 2019
Accepted: Mon 24, Jun 2019
Published: Mon 22, Jul 2019

Copyright

© 2023 Andrew  J. Kobets. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Hosting by Science Repository.
DOI: 10.31487/j.JSO.2019.02.09