Sono and photo stimulated Chlorine E6 nanocomposite in tumor-bearing mice: upcoming cancer treatment

Author Info

Ammar Yahya Kadhim Almamoori Gihan Hosny Abd Elsamie Metwally Aly Metwally Samir Ali

Corresponding Author

Samir Ali
Lecturer, Department of Applied Medical Chemistry, Medical Research Institute, Alexandria University, Egypt

A B S T R A C T

This study was directed at study the effectiveness of cancer targeted therapy using the activated Chlorine E6 nanocomposite (Nano-CE6). Study was applied on male Swiss albino mice, implanted with Ehrlich tumor (EAC) divided into six groups. Two energy sources were used; laser and Ultrasound. Results showed that Nano-CE6 is a potential sensitizer for photodynamic or sonodynamic treatment of tumor. NanoCE6 plays an important role in tumor growth inhibition and cell death induction. Activated Nano-CE6 with both infrared laser and ultrasound has a potential antitumor effect. The results indicated that (FA–NGO– CE6) could be used as a unique nanocomposite for cancer targeted therapy SPDT.

Article Info

Article Type

Research Article

Publication history

Received: Wed 03, Apr 2019
Accepted: Wed 15, May 2019
Published: Wed 17, Jul 2019

Copyright

© 2023 Samir Ali . This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Hosting by Science Repository.
DOI: 10.31487/j.RDI.2019.03.04