Malignancy of Aneurysmal Bone Cyst in Osteosarcoma and Angiosarcoma: Series of 2 Cases and Literature Review

Author Info

Sicilia Castresana Alejandro Pablo Mediavilla Santos Lydia Calvo Haro Jose Antonio Pérez Mañanes Rubén Cuervo Dehesa Miguel Vaquero Martín Francisco Javier

Corresponding Author

Sicilia Castresana Alejandro Pablo
Orthopaedic and Trauma Surgery Resident (R5), Hospital General Universitario Gregorio Marañón, Spain

A B S T R A C T

Aneurysmal bone cyst (ABC) is a rare benign bone tumor characteristic of the first decades of life. Malignization of ABC in the absence of risk factors such as radiotherapy is extremely rare, with few cases published in the literature. There are malignant tumors such as telangiectatic osteosarcoma with an initial clinical, radiological and anatomopathological resemblance that requires special attention in their differential diagnosis. We present two patients with an initial histologic diagnosis of ABC who developed true malignancy, in the absence of risk factors, into osteoblastic osteosarcoma and epithelioid angiosarcoma. In spite of its exceptional nature, in the presence of an aggressive type of ABC malignant degeneration should always be suspected and therefore, an open biopsy and wide resection performed for a correct diagnosis to avoid residual microscopic disease in case of aggressiveness. Epithelioid angiosarcoma from an ABC tumor malignancy has never been described before.

Article Info

Article Type

Case Report and Review of the Literature

Publication history

Received: Wed 05, Oct 2022
Accepted: Wed 19, Oct 2022
Published: Mon 28, Nov 2022

Copyright

© 2023 Sicilia Castresana Alejandro Pablo. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Hosting by Science Repository.
DOI: 10.31487/j.SCR.2022.11.02