Table 4: Adverse effects regarding sedation protocol.

 

TCI

(n=27)

Bolus

(n=27)

Total

(n=54)

p-value

HR > 125 bpm

2 (7%)

10 (37%)

12 (22%)

0.009

HR < 50 bpm

0 (0%)

1 (4%)

1(2%)

0.313

RRsys <90 mmHg

10 (37%)

2 (7%)

12 (22%)

0.080

RRsys <80 % of bl

17 (63%)

14 (52%)

31 (57%)

0.802

RRsys >120 % of bl

8 (30%)

15 (56%)

23 (43%)

0.070

SpO2 <90 % >10s

18 (69%)

18 (67%)

36 (68%)

ns

SpO2 <80 % >10s

4 (15%)

5 (19%)

9 (17%)

ns

Resp. rate <8/min

16 (59%)

16 (59%)

32 (59%)

ns

Expressed as number (n) and percentage (%).

TCI: Target-Controlled Infusion; HR: Heart Rate; BPM: Beats Per Minute; NS: Not Specified; BL: Baseline.