Table 1: Characteristics of study subjects.
|
Characteristics |
Subjects with Aseptic Loosening (n = 38) |
Subjects with PJI (n = 32) |
P-value |
|
Mean age (years) |
69.68 ± 9,31 (range 50 – 83) |
68.25 ± 10.86 (range 47 – 89) |
0.662 |
|
Sex |
|
|
0.808 |
|
Male |
16 (42%) |
12 (38%) |
|
|
Female |
22 (58%) |
20 (62%) |
|
|
Reason for arthroplasty |
|
|
|
|
Primary Osteoarthritis |
24 (63%) |
18 (56%) |
0.628 |
|
Inflammatory joint disorder |
4 (10%) |
0 |
0.119 |
|
Fracture / Trauma |
7 (18%) |
12 (38%) |
0.268 |
|
Congenital abnormalities |
2 (5%) |
2 (6%) |
1.000 |
|
Other |
1 (3%) |
0 |
1.000 |
|
Associated conditions |
|
|
|
|
Hypertension |
24 (63%) |
18 (56%) |
0.628 |
|
Diabetes mellitus |
10 (31%) |
11 (34%) |
0.601 |
|
Lipid abnormality |
9 (24%) |
7 (22%) |
1.000 |
|
Hypertriglyceridemia |
1 (3%) |
2 (6%) |
0.589 |
|
BMI |
28,74 ± 7,42 (range 20,76 – 47,75) |
28,89 ± 3,73 (range 22,83 – 34,77) |
0.921 |
|
Metabolic Syndrome |
9 (24%) |
7 (22%) |
1.000 |
|
Site of arthroplasty |
|
|
0.616 |
|
Hip |
25 (66%) |
23 (72%) |
|
|
Knee |
13 (34%) |
9 (28%) |
|
|
Cemented arthroplasties |
|
|
0.610 |
|
Cemented |
11 (29%) |
12 (38%) |
|
|
Uncemented |
27 (71%) |
20 (62%) |
|
|
Age of implant (months) |
105.72 ± 119.73 (range 1 – 336) |
74.94 ± 126.29 (range 2 – 432) |
0.306 |
|
Hip |
136.00 ± 135.02 |
105.18 ± 143.08 |
0.456 |
|
Knee |
45.17 ± 38.68 |
8.40 ± 3.57 |
0.007 |
|
PJI components |
|
|
|
|
Sinus tract |
0 |
7 |
0.003 |
|
Visible purulence |
0 |
15 |
<0.001 |
|
Positive cultures |
0 |
18 |
<0.001 |
|
Tissue inflammation |
0 |
21 |
<0.001 |
|
Surgical procedure |
|
|
|
|
One-stage exchange |
34 (89%) |
9 (28%) |
|
|
Two-stage exchange |
4 (11%) |
22 (69%) |
|
|
Arthrodesis |
|
1 (3%) |
|