Case

Age (years)

Histology

Interval

Clinical presentation

Therapy

Survival

Dawson et al. [4]

70

ILC

34 months

Altering bowel habit, constipation, anal discharge

Laparotomy and RT

?

Haberstich et al. [5]

78

IDC

At diagnosis

Painful anal tumefaction and blood loss with stools

Abdominoperineal resection and RT

Disease-free at 22 months follow-up

Nair et al. [6]

57

IDC

7 years

Alternating bowel habit, crampy lower abdominal pain, increased frequency of bowel movements

Colostomy and RT

?

Puglisi et al. [7]

92

ILC

4 years

Tenesmus and painful anal polypoid lesion

RT and hormonal therapy

3 years

Bochicchio et al. [8]

72

ILC

4 years

Constipation, tenesmus, fecal incontinence

Hartmann rectal amputation and RT

Few months after RT

Rengifo et al. [9]

78

IDC

27 months before diagnosis of BC

Rectal bleeding, weight loss, constipation

RT and hormonal therapy

?

Ruymbeke et al. [10]

65

ILC

4 years

Altering pattern of stool, intermittent fecal incontinence and tenesmus

RT and hormonal therapy and chemotherapy

Alive 15 months after diagnosis of anorectal metastasis