Table 2: eGFR, creatinine and potassium levels before and after 7 days of L-AMB treatment in all attacks and in attacks where nephrotoxicity developed.

All attacks (n=62)

 

Before L-AMB

treatment

After 7 days of L-AMB

treatment

P

eGFR (ml/min/1,73m2)

198.7 (165-263.3)

189 (148-237)

0.14

Creatinine (mg/dl)

0.32 (0.23-0.43)

0.37 (0.24-0.49)

0.074

Potassium (mmol/L)

4.04±0.61

3.64 ±0.65

<0.001

 

Attacks with nephrotoxicity (n=16)

 

eGFR (ml/min/1,73m2)

308.5 (230.70-340.40)

165.5 (94.90-196.20)

<0.001

Creatinine (mg/dl)

0.23 (0.17-0.32)

0.49 (0.27-0.67)

<0.001

Potassium (mmol/L)

4.12±0.56

3.77±0.68

>0.05

eGFR: Estimated glomerular filtration rate.