Table 2: Preoperative Levosimendan vs. Dobutamine groups in ventricular
dysfunction in patients subjected to aortic valve replacement.
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PARAMETER |
DOBUTAMINE |
LEVOSIMEDAN |
‘P’ value |
Cardiac frequency (lpm) |
61.6 ± 11.8 |
61.5 ± 16 |
0.61 * |
Systolic arterial pressure (mmHg) |
108.5 ± 16.8 |
96.9 ± 20 |
0.02 |
Mean pulmonary pressure (mmHg) |
22.9 ± 7.2 |
24.4 ± 9.1 |
0.82 * |
Pulmonary capillary pressure (cmH2O) |
16.4 ± 5.7 |
16.5 ± 6.8 |
0.92 |
Central venous pressure (cmH2O) |
11.1 ± 3.9 |
11.3 ±3.3 |
0.89 |
Cardiac output (L/min) |
3.2 ± 1.3 |
3.1 ± 1.1 |
0.83 |
Cardiac Index (L/min/m2) |
1.84 ± 0.7 |
1.77 ± 0.64 |
0.80 * |
Stroke volume (cc/min) |
52.5 ± 17.2 |
50.1 ± 13.3 |
0.56 |
Systolic index (cc/min/m2) |
31.4 ± 10.1 |
30.6 ± 9.1 |
0.73 |
Systematic resistance
(dinas.seg.cm-5) |
1877 ± 674 |
1743 ± 742 |
0.29 * |
LVWI (g.m/m2) |
40.9 ± 59 |
30.2 ± 29.7 |
0.03 * |
Pulmonary resistance (dinas.seg.cm-5) |
205 ± 133 |
240 ± 168 |
0.37 * |
LVEF (%) |
56.2 ± 11 |
56.4 ± 10 |
0.94 |
Systolic volume (cc) |
72.2 ± 45.8 |
66.2 ± 43 |
0.32 * |
Right ventricle (mm) |
155 ± 72.5 |
139 ± 82.2 |
0.15 * |
LVDD (mm) |
48.3 ± 8.4 |
47.4 ± 9.8 |
0.53 * |
LVSD (mm) |
33 ± 7.6 |
30.5 ± 9 |
0.92 |
IVS (mm) |
13.6 ± 2.16 |
13.3 ± 1.8 |
0.61 |
*Student T-test of
independent samples.