Table 2: Preoperative Levosimendan vs. Dobutamine groups in ventricular dysfunction in patients subjected to aortic valve replacement.


 

PARAMETER

DOBUTAMINE

LEVOSIMEDAN

‘P’ value

Cardiac frequency (lpm)

61.6 ± 11.8

61.5 ± 16

0.61 *

Systolic arterial pressure (mmHg)

108.5 ± 16.8

96.9 ± 20

0.02

Mean pulmonary pressure (mmHg)

22.9 ± 7.2

24.4 ± 9.1

0.82 *

Pulmonary capillary pressure (cmH2O)

16.4 ± 5.7

16.5 ± 6.8

0.92

Central venous pressure (cmH2O)

11.1 ± 3.9

11.3 ±3.3

0.89

Cardiac output (L/min)

3.2 ± 1.3

3.1 ± 1.1

0.83

Cardiac Index (L/min/m2)

1.84 ± 0.7

1.77 ± 0.64

0.80 *

Stroke volume (cc/min)

52.5 ± 17.2

50.1 ± 13.3

0.56

Systolic index (cc/min/m2)

31.4 ± 10.1

30.6 ± 9.1

0.73

Systematic resistance (dinas.seg.cm-5)

1877 ± 674

1743 ± 742

0.29 *

LVWI (g.m/m2)

40.9 ± 59

30.2 ± 29.7

0.03 *

Pulmonary resistance (dinas.seg.cm-5)

205 ± 133

240 ± 168

0.37 *

LVEF (%)

56.2 ± 11

56.4 ± 10

0.94

Systolic volume (cc)

72.2 ± 45.8

66.2 ± 43

0.32 *

Right ventricle (mm)

155 ± 72.5

139 ± 82.2

0.15 *

LVDD (mm)

48.3 ± 8.4

47.4 ± 9.8

0.53 *

LVSD (mm)

33 ± 7.6

30.5 ± 9

0.92

IVS (mm)

13.6 ± 2.16

13.3 ± 1.8

0.61

*Student T-test of independent samples.