Table 3: Postoperative Levosimendan vs. Dobutamine groups in ventricular
dysfunction in patients subjected to aortic valve replacement.
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PARAMETER |
DOBUTAMINE |
LEVOSIMEDAN |
‘P’ value |
Cardiac frequency (lpm) |
92.03 ± 16.4 |
92.7 ± 20.2 |
0.89 |
Systolic arterial pressure (mmHg) |
101.5 ± 13.7 |
102.3 ± 26 |
0.66 * |
Mean pulmonary pressure (mmHg) |
26.5 ± 5.1 |
24.9 ± 5.8 |
0.24 |
Pulmonary capillary pressure (cmH2O) |
17.03 ± 5.8 |
13.87 ± 2.9 |
0.01 |
Central venous pressure (cmH2O) |
13.87 ± 4.1 |
12.1 ± 2.9 |
0.06 |
Cardiac output (L/min) |
5.15 ± 1.5 |
5.5 ± 1.46 |
0.83 |
Cardiac Index (L/min/m2) |
3.0 ± 0.8 |
3.2 ± 0.9 |
0.32 |
Stroke volume (cc/min) |
58.5 ± 18.5 |
56.3 ± 18.4 |
0.65 |
Systolic index (cc/min/m2) |
36.1 ± 12.7 |
34.9 ± 19.7 |
0.56 * |
Systematic resistance
(dinas.seg.cm-5) |
969 ± 344 |
1018 ± 391 |
0.61 |
LVWI (g.m/m2) |
34 ± 20 |
35 ± 45 |
0.34 * |
Pulmonary resistance
(dinas.seg.cm-5) |
152 ± 78 |
195 ± 137 |
0.23 * |
LVEF (%) |
64.1 ± 13.6 |
57.6 ± 12.9 |
0.05 |
Systolic volume (cc) |
52 ± 36 |
53 ± 36 |
0.87 * |
Right ventricle (mm) |
88.7 ± 48.4 |
106.7 ± 52.2 |
0.17 |
LVDD (mm) |
42.3 ± 6.9 |
42.5 ± 9.0 |
0.69 * |
LVSD (mm) |
28.8 ± 7.6 |
30.5 ± 9.0 |
0.67 * |
IVS (mm) |
13.2 ± 2.4 |
13.6 ± 2.5 |
0.56 |
|
13.2 ± 2.7 |
13.3 ± 2.5 |
0.92 |
*Student T-test of
independent samples.