Table 1: Effects of formoterol and AR42 treatments on food intake, body weight and tumor content in tumor-bearing rats.

Parameters

 

 

Experimental groups

 

C

T

T+F

T+A

T+F+A

IBW

176 ± 5

178 ± 3

180 ± 2

176 ± 11

177 ± 4 

FBW

216 ± 6

182 ± 6 ##

189 ± 6

172 ± 6

174 ± 4

DBW

40 ± 4

4 ± 5 ###

10 ± 5

-5 ± 5

-2,4 ± 4

Food intake

71 ± 2

63 ± 3 #

69 ± 1

51 ± 4 *

55 ± 5

Carcass

87 ± 3

78 ± 1 ##

80 ± 1

76 ± 2

75 ± 2

GIT

10527 ± 453

6756 ± 316 ###

6480  ± 296

8043  ± 699

7546 ± 417

Tumor

 

 

 

 

 

 

Volume (mL)

-

41 ± 1

46 ± 4

40 ± 3

39 ± 4

Total cell number (106)

-

5337 ± 539

4533 ± 386

3289 ± 458  *

3438 ± 482 *

Results are mean ± SEM for the number of animals: C (6), T (7), T+F (5), T+A (4), T+F+A (7). IBW: Initial Body Weight and FBW: Final Body Weight are expressed in g. Food intake is expressed as g/100g IBW and refers to the cumulative intake (7 days). Carcass is expressed in g/100 g IBW. GIT: Gastrointestinal Tract is expressed in mg/100 g IBW. Values that are significantly different by the Student’s t-test from the control group (C) are indicated by # p <0.05, ## p < 0.01, ### p < 0.001, and from the tumor non-treated animal group (T) are indicated by * p <0.05.

C: rats without tumor; T: Tumor-bearing rats; T+F: Treated with Formoterol; T+A: Treated with AR42; T+F+A: Treated with both Formoterol and AR42.