Table 3: Effects of formoterol and AR42 treatments on grip force in tumor-bearing rats.

Parameters

 

 

Experimental groups

 

C

T

      T+F

T+A

T+F+A

Grip force day 0

340 ± 11

343 ± 12

342 ± 11

286 ± 18 *

322 ± 27

Grip force day 7

426 ± 20

357 ± 14 ##

449 ± 11 ***

257 ± 12 **

377 ± 13

D grip force

86 ± 19

15 ± 21 #

107 ± 11 ***

-29 ± 23

55 ± 24

Results are mean ± SEM for the number of animals: C (12), T (13), T+F (13), T+A (4), T+F+A (7). D grip force was calculated as [(grip force day 7- grip force day 0)/ IBW] * 100. Values that are significantly different by the Student’s t-test from the control group (C) are indicated by # p <0.05, ## p < 0.01, ### p < 0.001, and from the tumor non-treated animal group (T) are indicated by * p <0.05, ** p <0.01, *** p < 0.001.

C: rats without tumor; T: Tumor-bearing rats; T+F: Treated with Formoterol; T+A: Treated with AR42; T+F+A: Treated with both Formoterol and AR42.