Table 6: Effect of the aqueous extract of Manihot esculenta on oxidative stress markers.

 

TN

TP

ME

Serum

 

 

 

SOD units/g of proteins

8.91 ± 0.71

5.32 ± 0.86#

9.06 ± 1.22*

Catalase mmol of H2O2/min/g proteins

58.43 ± 5.12

37.43 ± 4.69#

49.23 ± 6.07**

GSH (umol/ml)

41.23 ± 3.07

26.33 ± 2.56#

30.74 ± 2.57

TBARS (umol/ml)

3.16 ± 0.52

6.32 ± 1.06#

4.41 ± 1.17*

NO (mmol/ml)

102.47 ± 9.02

74.43 ± 4.76##

83.55 ± 4.47*

Aorta

 

 

 

SOD units/g of proteins

6.74 ± 0.56

5.19 ± 0.72#

5.89 ± 1.07

Catalase mmol of H2O2/min/g proteins

34.28 ± 3.06

28.94 ± 2.47#

29.78 ± 3.19

GSH (umol/mg tissue)

29.83 ± 3.16

23.61 ± 2.11#

26.73 ± 2.64

TBARS (umol/mg tissue)

2.45 ± 0.36

4.05 ± 0.57#

3.04 ± 0.49*

NO (mmol/mg tissue)

146.54 ± 5.62

106.21 ± 4.03##

136.31 ± 4.23*

TN: group of rats receiving distilled water, TP: group of rats receiving concomitantly high fat/high sucrose diet and ethanol 40°, ME: group treated with Manihot esculenta leaf aqueous extract in addition to high fat/high sucrose diet and ethanol 40°. # p <0.05; ## p <0.001 compared to TN group; and * p <0.05; ** p <0.01 compared to the TP group.