ACUTE PHASE

CHRONIC PHASE

KATAYAMA’S FEVER

URTICARIA

MYALGIA

HEADACHE

DIARRHEA

EOSINOPHILIA (causing encephalitis without vasculitis)

ABDOMINAL PAIN

INAPETENCE

DIARRHEA

IRON DEFICIENCY ANEMIA

NO HEMATIC CHANGES (no eosinophilia)

NORMAL TRANSAMINASES

SYMMERS’ FIBROSIS - occlusion of the portal vein (non-cirrhotic) by collagen deposition along the stellate cells of the periportal space

SPLENOMEGALY

SHUNT PORTO CAVA

GLOMERULOPATHY (proteinuria with nephrotic syndrome)