Study

Pt

(n)

Bone (n)

or

Soft tissue (n)

Imaging-guidance

Gauge

of needle

Passes

(n)

Diagnostic results

after CNB (%)

Diagnostic accuracy after surgical treatment

Complications

Zornoza, 1982 [35]

42

Soft tissue

CT or US

18 or 14

>2

83% (35/42)

-

None

Skrzynsky, 1996 [14]

62

Bone (17)

Soft tissue (45)

None

-

3-6

84% (52/62)

DA 100% in Bone

DA 78% in Soft tissue

Track infection (1)

Schweitzer, 1996 [17]

138

Bone

FS

12 or 18

2-3

98% (135/138)

-

-

Heslin, 1997 [19]

60

Soft tissue

None

-

-

93% (56/60)

Cc in diagnosis malignancy (56/56)

Cc in diagnosing grade (40/56)

-

Dupuy, 1998 [31]

176

Bone

Soft tissue

CT

14

-

-

Cc 93% (164/176)

Hematoma (1)

Vasovagal symptom (1)

Yao, 1999 [33]

141

Bone (56)

Soft tissue (85)

CT (122)

FS (13)

US (4)

None (2)

12-14

14-18

3-8

Bone 75% (42/56)

Soft tissue: 82% (70/85)

Cc 73% (41/56) in Bone

Cc 75% (64/85) in Soft tissue

None

Welker, 2000 [32]

161

Bone (83)

Soft tissue (78)

None (90)

CT (55)

FS (28)

14-17 / 8-11

14-15

3-5

88% (142/161)

DA nature of the lesion 92%

DA grade 89%

DA specific diagnosis 73%

Hematoma (1)

Drainage (1)

Konermann, 2000 [38]

65

Bone

Soft tissue

US

14

3-5

94% (61/65)

-

None

Torriani, 2002 [36]

65

Bone (27)

Soft tissue (38)

US

14

>5

96% (63/65)

Cc 97% (47/48)

None

Jelinek, 2002 [22]

110

Bone

CT (85)

FS (25)

7-14 / 12-16

14-18

3-10

88% (97/110)

Cc 98% (89/91) in diagnosis malignancy

Cc 91% (83/91) in diagnosing grade

Hematoma (1)

Issakov, 2003 [40]

215

Bone (135)

Soft tissue (80)

CT

11-14

14-18

3-10

Bone 87% (118/135)

Soft tissue 94% (75/80)

-

Hematoma (3)

Ray-Coquard, 2003 [30]

110

Soft tissue

CT or US

14

4

94% (103/110)

Cc 88% (91/103)

Bleeding (1)

Hematoma (6)

Yang, 2004 [15]

50

Bone

Soft tissue

-

-

6

98% (49/50)

DA nature of the lesion 94% (47/50)

DA specific diagnosis 86% (43/50)

DA histologic grading 87% (27/31)

DA histologic typing 92% (46/50)

None

Mitsuyoshi, 2006 [18]

163

Bone (91)

Soft tissue (72)

None (119)

CT (44)

16

-

>2

Bone 88% (80/91)

Soft tissue 88% (63/72)

No guidance: 85%

CT-guided: 93%

Cc 88% (126/143)

Hematoma (1)

Battaglia, 2007 [44]

164

Soft tissue

US

14-18 or 13-14

3-4

D 90% (148/164)

-

-

Sung, 2009 [41]

309

Bone (167)

Soft tissue (142)

US (151)

CT (89)

FS (69)

-

-

Bone 92%

Soft tissue 89%

In 185 surgically treated

DA 89% in Bone

DA 79% in Soft tissue

-

Kasraeian, 2010 [12]

57

Soft tissue

None

14

3-5

86% (49/57)

Cc 81%

None

Adams, 2010 [27]

233

Bone (16)

Soft tissue (217)

None

-

1-10

94% (219/233)

Cc 97% in diagnosing malignancy

Cc 81% in diagnosis and grade

None

Strauss, 2010 [37]

530

Soft tissue

None

-

>4

93% (493/530)

In 371 surgically treated

DA 98% in diagnosing sarcomas

DA 86% in diagnosing grade

DA 88% in diagnosing benign subtype

DA 88% in diagnosing malignant subtype

Hematoma (1)

Bleeding (1)

Yang, 2010 [29]

508

Bone (272)

Soft tissue (236)

CT (339)

US (169)

16 or 20

1-6

Bone 87% (237/272)

Soft tissue 96% (226/236)

-

-

Rimondi, 2011 [28]

2027

Bone

CT

8/15

>2

77% (1567/2027)

-

Transient paresis (18)

Haematoma (4)

Peer, 2011 [42]

223

Soft tissue

US

14-18

3-10

95% (211/223)

In 113 surgically treated

DA 100% in diagnosing malignancy

-

Pohlig, 2012 [13]

46

Bone (33)

Soft tissue (13)

CT or US 

14

3-5

Bone 100% (33/33)

Soft tissue 92% (12/13)

DA 100% in Bone

DA 85% in Soft tissue

None

Seng, 2013 [43]

134

Bone

Soft tissue

CT

-

3-5

95% (127/134)

Cc 88% (118/134)

DA 94% (31/33) in Bone

DA 96% (71/74) in Soft tissue

Wound bruising

Nouh, 2014 [34]

49

Bone

CT

16-18 or 12-15

6

88% (43/49)

Cc 1005 (29/29)

None

Trieu, 2016 [26]

1131

Bone (380)

Soft tissue (751)

CT

14 or 18

-

Bone 88% (334/380)

Soft tissue 94% (703/751)

DA 81% in Bone

DA 83% in Soft tissue

0.8%

Walker, 2018 [39]

105

Soft tissue

None

-

-

-

In 69 surgically treated

Cc 87%

DA 94% nature of the lesion

Hematoma (2)

Bleeding (1)

Current study

722

Bone (400)

Soft tissue (322)

FS (376)

US (322)

CT (24)

8 in Bone

14 in Soft tissue

6-10

Bone 97% (366/376)

Soft tissue 94% (304/322)

Cc 170/173 (98%) in Bone

Cc 113/119 (95%) in Soft tissue

None