Table 3: Correlation of Ki-67 and cyclinD1 expression levels with clinicopathological variables in MPNST.
|
Clinical parameters |
|
Ki-67 |
|
CyclinD1 |
||||
|
Positive expression |
Negative expression |
χ2 |
P |
Positive expression |
Negative expression |
χ2 |
P |
|
|
Gender |
|
|
0.923 |
0.337 |
|
|
1.260 |
0.262 |
|
Male (35) |
18 |
17 |
|
|
8 |
27 |
|
|
|
Female (28) |
11 |
17 |
|
10 |
18 |
|
||
|
Age |
|
|
0.246 |
0.620 |
|
|
0.431 |
0.512 |
|
>=40 years (39) |
17 |
22 |
|
|
10 |
29 |
|
|
|
<40 years (24) |
12 |
12 |
|
8 |
16 |
|
||
|
NF1 No (58) Yes (5) Tumor site |
24 5 |
34 0 |
6.367
1.732 |
0.012
0.421 |
16 2 |
42 3 |
0.348
0.918 |
0.555
0.632 |
|
Head and neck (10) |
4 |
6 |
|
|
2 |
8 |
|
|
|
Trunk (26) |
10 |
16 |
|
9 |
17 |
|
||
|
Extremity (27) |
15 |
12 |
|
7 |
20 |
|
||
|
Tumor size |
|
|
0.410 |
0.815 |
|
|
1.423 |
0.491 |
|
<5cm (24) |
10 |
14 |
|
|
5 |
19 |
|
|
|
5-10cm (22) |
11 |
11 |
|
7 |
15 |
|
||
|
>10cm (16) |
8 |
8 |
|
6 |
10 |
|
||
|
AJCC stage |
|
|
1.972 |
0.578 |
|
|
5.649 |
0.130 |
|
Ⅰ-Ⅱ (39) Ⅲ-Ⅳ (21) |
16 12 |
23 9 |
|
|
11 6 |
28 15 |
|
|
|
Radiotherapy |
|
|
0.430 |
0.512 |
|
|
0.506 |
0.477 |
|
Yes (25) |
12 |
13 |
|
|
9 |
16 |
|
|
|
No (33) |
13 |
20 |
|
9 |
24 |
|
||
|
Chemotherapy |
|
|
1.384 |
0.239 |
|
|
0.189 |
0.664 |
|
Yes (25) |
9 |
16 |
|
|
7 |
18 |
|
|
|
No (33) |
17 |
16 |
|
11 |
22 |
|
||
|
Surgical type |
|
|
0.047 |
0.828 |
|
|
2.219 |
0.136 |
|
Wide resection (40) |
18 |
22 |
|
|
14 |
26 |
|
|
|
Subtotal resection (23) |
11 |
12 |
|
4
|
19
|
|
||
|
Recurrence |
|
|
0.695 |
0.405 |
|
|
0.110 |
0.741 |
|
Yes (40) |
20 |
20 |
|
|
12 |
28 |
|
|
|
No (23) |
9 |
14 |
|
6 |
17 |
|
||
|
Metastasis |
|
|
0.246 |
0.620 |
|
|
0.431 |
0.512 |
|
Yes (24) |
12 |
12 |
|
|
8 |
16 |
|
|
|
No (39) |
17 |
22 |
|
10 |
29 |
|
||