Table 1: Patient characteristics: comparison between non-cirrhotic and cirrhotic patients.
|
|
Non-cirrhotic n=101 |
Cirrhotic n=382 |
P value |
||||
|
N |
|
N |
|
|
|||
|
Age in years (mean, SD) |
101 |
67.16(11.3) |
382 |
63.85(9.14) |
P=0.001 |
||
|
Gender (males) |
101 |
77(76%) |
382 |
327(86%) |
P=0.03 |
||
|
Smoking |
Current |
98 |
22(22.4%) |
373 |
123(33%) |
P=0.131 |
|
|
Past |
17(17.3%) |
58(15.5%) |
|||||
|
Never |
59(60%) |
192(51.5%) |
|||||
|
BMI (Kg/m2)(mean SD) |
101 |
26.11(5.1) |
381 |
27.53(4.8) |
P=0.012 |
||
|
Diabetes |
Yes |
101 |
31(30.7%) |
382 |
125(32.7%) |
P=0.698 |
|
|
Etiology
|
NAFLD |
101 |
26(25.7%) |
382 |
66(17.3%) |
P<0.001 |
|
|
Alcohol |
23(22.8%) |
146(38%) |
|||||
|
HCV |
20(19.8%) |
85(22.3%) |
|||||
|
HBV |
8(7.9%) |
25 (6.5%) |
|||||
|
HCV+ alcohol |
2(2%) |
40(10.5%) |
|||||
|
Other* |
10(9.9%) |
14(3.7%) |
|||||
|
Unknown |
12(11.9%) |
6(1.6%) |
|||||
|
ECOG PS ≥2 |
101 |
5(8%) |
382 |
47(16%) |
P=0.078 |
||
|
Liver function |
Child Pugh |
A |
91 |
79 (86.8%) |
345 |
210(60.9%) |
P<0.001 |
|
B |
12 (13.2%) |
112(32.5) |
|||||
|
C |
0 |
23(6.7%) |
|||||
|
MELD (median and IQR) |
100 |
8 (6-11) |
380 |
9.5 (7-12) |
P<0.02 |
||
Values are presented as n (%), mean (SD, standard deviation), median (IQR, interquartile range).
The p values apply to the cirrhotic versus non-cirrhotic group. P value was assumed to be significant when <0.05.
N represents the patients’ number with available data.
HCV: Hepatitis C Virus; HBV: Hepatitis B Virus; NAFLD: Non-Alcoholic Liver Disease; Other* include: hemochromatosis, primary biliary cholangitis, and autoimmune hepatitis; ECOG PS: Eastern Cooperative Oncology Group Performance Status; MELD: Model for End-stage Liver Disease.