Table 3: Correlation between Livin expression and clinicopathological features of the primary tumors.

Features

Number of cases (%)

Livin-expression in the primary tumors

 

Negative (0), weak (1) vs. moderate (2+), Strong (3+)

Negative, weak

Moderate, strong

P-value

Age (years)

 

 

 

0.73

< 49 years

46 (59%)

31(68%)

15(32%)

 

≥ 49 years

32(41%)

22(68.7%)

10(31.3%)

 

Site of tumor

 

 

 

0.645

Right

43 (55%)

24(55.8%)

19(44.2%)

 

Left

35(45%)

22(62.9%)

13(37.1%)

 

Histological Type

 

 

 

0.374

Invasive ductal carcinoma

69(89%)

40(58%)

29(42%)

 

Mucinous carcinoma

3(4%)

1(33.3%)

2(66.7%)

 

Invasive lobular carcinoma

3(4%)

3(100%)

0(0%)

 

Papillary carcinoma

1(1%)

1(100%)

0(100%)

 

Secretory carcinoma

1(1%)

1(100%)

0(100%)

 

Cribriform carcinoma

1(1%)

0(100%)

1(100%)

 

Histological Grades

 

 

 

0.852

G1

13(17%)

8(61.5%)

5(38.5%)

 

G2

48(61%)

27(56.3%)

21(43.8%)

 

G3

17(22%)

11(64.7%)

6(35.3%)

 

Stage

 

 

 

0.47

I

6(8%)

2(33.3%)

4(66.7%)

 

IIA

23(29%)

15(65.2%)

8(34.8%)

 

IIB

13(17%)

6(46.2%)

7(53.8%)

 

III

1(1%)

0(0%)

1(100%)

 

IIIA

18(23%)

11(61.1%)

7(38.9%)

 

IIIB

1(1%)

1(100%)

0(0%)

 

IV

16(21%)

11(68.8%)

5(31.3%)

 

Primary Tumor

 

 

 

0.584

T1

6(8%)

2(33.3%)

4(66.7%)

 

T2

44(56%)

24(54.5%)

20(45.5%)

 

T3

28(36%)

12(42.8%)

16(75.2%)

 

Lymph node involvement

 

 

 

0.820

No

35(45%)

20(57.1%)

15(42.9%)

 

yes

43(55%)

26(60.5%)

17(39.5%)

 

Distance Metastases

 

 

 

0.410

No

62(79%)

35(56.5%)

27(43.5%)

 

yes

16(21%)

11(68.8%)

5(31.3%)

 

Chemotherapy

 

 

 

0.694

No

7(9%)

5(71.4%)

2(28.6%)

 

Yes

71(91%)

41(57.7%)

30(42.3%)

 

Radiotherapy

 

 

 

0.330

No

26(33%)

13(50%)

13(50%)

 

yes

52(67%)

33(63.5%)

19(36.5%)

 

Recurrence

 

 

 

0.683

No

70(90%)

42(60%)

28(40%)

 

yes

6(8%)

3(50%)

3(50%)

 

Estrogen

 

 

 

0.353

No

32(41%)

17(53.1%)

15(46.9%)

 

yes

45(58%)

29(64.4%)

16(35.6%)

 

Progesterone

 

 

 

0.488

No

31(40%)

17(45.2%)

14(54.8%)

 

yes

46(59%)

29(63.0%)

17(37%)

 

Her-2

 

 

 

0.414

No

59(76%)

37(62.7%)

22(37.3%)

 

yes

18(23%)

9(50%)

9(50%)

 

Multifocality

 

 

 

1.000

No

70(90%)

41(58.6%)

29(41.4%)

 

yes

8(10%)

5(62.5%)

3(37.5%)

 

Free surgical margin

 

 

 

0.570

No

16(21%)

8(50%)

8(50%)

 

yes

20(26%)

24(38.7%)

38(61.3%)

 

Vascular Invasion

 

 

 

0.299

No

58(74%)

32(55.2%)

26(44.8%)

 

yes

20(26%)

14(70%)

6(30%)

 

Positive family history

 

 

 

0.025

No

74(95%)

46(62.2%)

28(37.8%)

 

yes

4(5%)

0(0%)

4(100%)

 

Hormone replacement Therapy

 

 

 

0.640

No

29(37%)

16(55.2%)

13(44.8%)

 

Yes

49(63%)

30(61.2%)

19(38.8%)