Table 3:
Correlation between Livin expression and clinicopathological features of the
primary tumors.
Features |
Number of cases (%) |
Livin-expression
in the primary tumors |
|
|
Negative (0), weak (1) vs. moderate (2+),
Strong (3+) |
||||
Negative, weak |
Moderate, strong |
P-value |
||
Age (years) |
|
|
|
0.73 |
< 49 years |
46 (59%) |
31(68%) |
15(32%) |
|
≥ 49 years |
32(41%) |
22(68.7%) |
10(31.3%) |
|
Site of tumor |
|
|
|
0.645 |
Right |
43 (55%) |
24(55.8%) |
19(44.2%) |
|
Left |
35(45%) |
22(62.9%) |
13(37.1%) |
|
Histological Type |
|
|
|
0.374 |
Invasive ductal carcinoma |
69(89%) |
40(58%) |
29(42%) |
|
Mucinous carcinoma |
3(4%) |
1(33.3%) |
2(66.7%) |
|
Invasive lobular carcinoma |
3(4%) |
3(100%) |
0(0%) |
|
Papillary carcinoma |
1(1%) |
1(100%) |
0(100%) |
|
Secretory carcinoma |
1(1%) |
1(100%) |
0(100%) |
|
Cribriform carcinoma |
1(1%) |
0(100%) |
1(100%) |
|
Histological Grades |
|
|
|
0.852 |
G1 |
13(17%) |
8(61.5%) |
5(38.5%) |
|
G2 |
48(61%) |
27(56.3%) |
21(43.8%) |
|
G3 |
17(22%) |
11(64.7%) |
6(35.3%) |
|
Stage |
|
|
|
0.47 |
I |
6(8%) |
2(33.3%) |
4(66.7%) |
|
IIA |
23(29%) |
15(65.2%) |
8(34.8%) |
|
IIB |
13(17%) |
6(46.2%) |
7(53.8%) |
|
III |
1(1%) |
0(0%) |
1(100%) |
|
IIIA |
18(23%) |
11(61.1%) |
7(38.9%) |
|
IIIB |
1(1%) |
1(100%) |
0(0%) |
|
IV |
16(21%) |
11(68.8%) |
5(31.3%) |
|
Primary Tumor |
|
|
|
0.584 |
T1 |
6(8%) |
2(33.3%) |
4(66.7%) |
|
T2 |
44(56%) |
24(54.5%) |
20(45.5%) |
|
T3 |
28(36%) |
12(42.8%) |
16(75.2%) |
|
Lymph node involvement |
|
|
|
0.820 |
No |
35(45%) |
20(57.1%) |
15(42.9%) |
|
yes |
43(55%) |
26(60.5%) |
17(39.5%) |
|
Distance Metastases |
|
|
|
0.410 |
No |
62(79%) |
35(56.5%) |
27(43.5%) |
|
yes |
16(21%) |
11(68.8%) |
5(31.3%) |
|
Chemotherapy |
|
|
|
0.694 |
No |
7(9%) |
5(71.4%) |
2(28.6%) |
|
Yes |
71(91%) |
41(57.7%) |
30(42.3%) |
|
Radiotherapy |
|
|
|
0.330 |
No |
26(33%) |
13(50%) |
13(50%) |
|
yes |
52(67%) |
33(63.5%) |
19(36.5%) |
|
Recurrence |
|
|
|
0.683 |
No |
70(90%) |
42(60%) |
28(40%) |
|
yes |
6(8%) |
3(50%) |
3(50%) |
|
Estrogen |
|
|
|
0.353 |
No |
32(41%) |
17(53.1%) |
15(46.9%) |
|
yes |
45(58%) |
29(64.4%) |
16(35.6%) |
|
Progesterone |
|
|
|
0.488 |
No |
31(40%) |
17(45.2%) |
14(54.8%) |
|
yes |
46(59%) |
29(63.0%) |
17(37%) |
|
Her-2 |
|
|
|
0.414 |
No |
59(76%) |
37(62.7%) |
22(37.3%) |
|
yes |
18(23%) |
9(50%) |
9(50%) |
|
Multifocality |
|
|
|
1.000 |
No |
70(90%) |
41(58.6%) |
29(41.4%) |
|
yes |
8(10%) |
5(62.5%) |
3(37.5%) |
|
Free surgical margin |
|
|
|
0.570 |
No |
16(21%) |
8(50%) |
8(50%) |
|
yes |
20(26%) |
24(38.7%) |
38(61.3%) |
|
Vascular Invasion |
|
|
|
0.299 |
No |
58(74%) |
32(55.2%) |
26(44.8%) |
|
yes |
20(26%) |
14(70%) |
6(30%) |
|
Positive family history |
|
|
|
0.025 |
No |
74(95%) |
46(62.2%) |
28(37.8%) |
|
yes |
4(5%) |
0(0%) |
4(100%) |
|
Hormone replacement Therapy |
|
|
|
0.640 |
No |
29(37%) |
16(55.2%) |
13(44.8%) |
|
Yes |
49(63%) |
30(61.2%) |
19(38.8%) |
|