Table
1: Pre- and post-operative
characteristics of patients with early-stage Endometrial Cancer.
|
|
Patients that underwent HT+DA+BSGC (N= 8) |
Patients that underwent HT+DA+BSGC+ LNF (N=10) |
p |
|
||||||||
|
QUALITATIVE VARIABLES |
|
|
||||||||||
|
ASSOCIATED RF |
% |
% |
p |
|
||||||||
|
None |
50 |
70 |
>0,05 |
|
||||||||
|
HTA |
12,5 |
30 |
|
|
||||||||
|
DM |
12,5 |
0 |
|
|
||||||||
|
DM y HTA |
25 |
0 |
|
|
||||||||
|
SOP |
0 |
0 |
|
|
||||||||
|
TOBACCO USAGE |
12,5 |
20 |
>0,05 |
|
||||||||
|
BMI (kg/m2) |
|
|
>0,05 |
|
||||||||
|
< 25 |
37,5 |
50 |
|
|
||||||||
|
25-29,9 |
25 |
20 |
|
|
||||||||
|
>30 |
37,5 |
30 |
|
|
||||||||
|
HEREDITARY SD |
12,5 |
0 |
>0,05 |
|
||||||||
|
THS |
12,5 |
0 |
>0,05 |
|
||||||||
|
TREATMENTS WITH TMX |
0 |
0 |
>0,05 |
|
||||||||
|
GLOBAL DETECTION SN |
62,5 |
90 |
p>0,05 |
|
||||||||
|
BILATERAL DETECTION SN |
80 |
66,7 |
>0,05 |
|
||||||||
|
LOCATION RIGHT SN |
|
|
>0,05 |
|
||||||||
|
Common Iliac Artery Bifurcation |
80 |
57,1 |
|
|
||||||||
|
External Iliac Artery |
20 |
28,6 |
|
|
||||||||
|
Obturator Fossa |
0 |
14,3 |
|
|
||||||||
|
LOCATION RIGHT SN |
|
|
>0,05 |
|
||||||||
|
Common Iliac Artery Bifurcation |
33,3 |
71,4 |
|
|
||||||||
|
External Iliac Artery |
33,3 |
28,6 |
|
|
||||||||
|
Obturator Fossa |
33,3 |
0 |
|
|
||||||||
|
RIGHT SN STAGE |
|
|
|
|
||||||||
|
Negative |
100 |
100 |
|
|
||||||||
|
Positive |
0 |
0 |
|
|
||||||||
|
LEFT SN STAGE |
|
|
|
|
||||||||
|
Negative |
100 |
100 |
|
|
||||||||
|
Positive |
0 |
0 |
|
|
||||||||
|
ADYUVANT QT |
0 |
20 |
>0,05 |
|
||||||||
|
ADYUVANT RT |
37,5 |
88,9 |
>0,05 |
|
||||||||
|
TIPE RT |
|
|
>0,05 |
|
||||||||
|
RTE |
33,3 |
75 |
|
|
||||||||
|
BT |
66,7 |
25 |
|
|
||||||||
|
HISTOLOGY |
|
|
>0,05 |
|
||||||||
|
Tipo I Endometrioid |
100 |
70 |
|
|
||||||||
|
Tipo II no endometroid |
0 |
30 |
|
|
||||||||
|
HISTOLOGICAL DEGREE |
|
|
>0,05 |
|
||||||||
|
G1 |
37,5 |
30 |
|
|
||||||||
|
G2 |
62,5 |
30 |
|
|
||||||||
|
G3 |
0 |
40 |
|
|
||||||||
|
LVI |
25 |
30 |
>0,05 |
|
||||||||
|
MELF PATTERN |
12,5 |
20 |
>0,05 |
|
||||||||
|
MOLECULAR PROFILE |
|
** |
0,019 |
|
||||||||
|
POLE mut |
0 |
0 |
|
|
||||||||
|
MMrd |
37,5 |
60 |
|
|
||||||||
|
NSMP |
62,5 |
0 |
|
|
||||||||
|
P53abn |
0 |
30 |
|
|
||||||||
|
|
|
|
|
|
||||||||
|
MIOMETRIAL INFILTRATION |
|
|
>0,05 |
|
||||||||
|
<50% |
100 |
60 |
|
|
||||||||
|
>50% |
60 |
40 |
|
|
||||||||
|
PRE-OPERATIVE FIGO STAGE |
|
|
0,015 |
|
||||||||
|
IA |
87,5 |
20 |
|
|
||||||||
|
IB |
12,5 |
80 |
|
|
||||||||
|
POST-OPERATIVE FIGO STAGE |
|
|
>0,05 |
|
||||||||
|
IA |
87,5 |
40 |
|
|
||||||||
|
IB |
|
30 |
|
|
||||||||
|
II |
12,5 |
20 |
|
|
||||||||
|
IIIA |
|
10 |
|
|
||||||||
|
SURGICAL COMPLICATIONS |
12,5 |
40 |
>0,05 |
|
||||||||
|
ADVERSE EVENTS |
0 |
70 |
0,02 |
|
||||||||
|
MORTALITY |
0 |
10 |
0,05 |
|
||||||||
|
QUANTITATIVE
VARIABLES |
|
|||||||||||
|
|
N |
Min |
Max |
X |
DS |
N |
Min |
Max |
X |
DS |
p |
|
|
AGE OF Dx (years) |
8 |
45 |
80 |
62,62 |
12,78 |
10 |
53 |
74 |
65,80 |
7,26 |
>0,05 |
|
|
AGE OF MENARCHE (years) |
8 |
11 |
13 |
12,38 |
,74 |
10 |
11 |
15 |
12,80 |
1,22 |
>0,05 |
|
|
MENOPAUSE AGE (years) |
6 |
42 |
69 |
53,5 |
8,68 |
9 |
45,0 |
55 |
50,44 |
3,28 |
>0,05 |
|
|
BMI (kg/m2) |
8 |
22,77 |
31,18 |
27,99 |
3,30 |
10 |
21,19 |
33,95 |
26,63 |
4,22 |
>0,05 |
|
|
DURATION (minutes) SURGERY |
8 |
100 |
150 |
115,6 |
17,61 |
10 |
205 |
300 |
243,5 |
33,0 |
>0,05 |
|
|
TIME (minutes) FOR DETECTION SN |
5 |
14 |
20,0 |
16,4 |
2,50 |
9 |
14 |
20 |
16,22 |
2,048 |
>0,05 |
|
|
TUMOR SIZE |
8 |
11 |
37,0 |
24,25 |
8,94 |
10 |
20 |
70 |
38,90 |
15,84 |
>0,05 |
|
|
Nº RIGHT SN |
8 |
0 |
1 |
,63 |
,51 |
9 |
,00 |
1,0 |
,66 |
,500 |
|
|
|
Nº LEFT SN |
8 |
0 |
1 |
,38 |
,51 |
10 |
0 |
1 |
,70 |
,48 |
|
|
|
Nº OF n-SLN RIGTH PELVIS |
0 |
|
|
|
|
10 |
0 |
2 |
,90 |
,56 |
|
|
|
Nº OF TOTAL n-SLN RIGHT PELVIS |
6 |
0 |
1 |
,83 |
,40 |
10 |
5 |
13 |
7,20 |
3,01 |
|
|
|
Nº OF n-SLN AFFECTED IN RIGHT PELVIS |
5 |
0 |
0 |
,00 |
,00 |
10 |
5 |
14 |
7,90 |
2,96 |
|
|
|
Nº OF n-SLN LEFT PELVIS |
0 |
|
|
|
|
10 |
0 |
0 |
,00 |
,00 |
|
|
|
Nº OF TOTAL n-SLN LEFT PELVIS |
4 |
0 |
1 |
,75 |
,500 |
10 |
3 |
10 |
7,40 |
2,59 |
|
|
|
Nº OF n-SLN AFFECTED LEFT PELVIS |
3 |
0 |
0 |
,00 |
,000 |
10 |
4 |
11 |
8,30 |
2,54 |
|
|
|
Nº OF n-SLN PARAORTICS |
0 |
|
|
|
|
10 |
0 |
0 |
,00 |
,00 |
|
|
|
Nº OF TOTAL n-SLN PARAAORTICS |
0 |
|
|
|
|
10 |
0 |
1 |
,20 |
,42 |
|
|
|
Nº OF n-SLN PARAAORTICS AFFECTED |
0 |
|
|
|
|
10 |
1 |
20 |
10,4 |
6,58 |
|
|
Qualitative
variables are expressed in number and percentage. Quantitative variables are
expressed as minimum value, maximum value, mean (X) and standard deviation
(N=sample size).
RF: Risk Factors; HTN: Arterial Hypertension; DM:
Diabetes Mellitus; PCOS: Polycystic Ovary Syndrome; SD: Syndromes; HRT: Hormone
Replacement Treatment; TMX: Tamoxifen; SN: Sentinel Node; n-SLN: non-Sentinel
Node; CT: Chemotherapy; RT: Radiotherapy; IVSI: Invasion of the lympho-vascular
space; MELF: Microcystic, Elongated and Fragmented; MSI: Unstable
Microsatellites; Dx: Diagnosis.
**
One patient (10%) did not present differentiation for epithelial, muscular or
endometrial stromal tumor, with FAF1/EPS15 Genetic Fusion.