Table 2: Important conditions to be evaluated associated to surgical management of LABC.

General

Category

Variables

 

Tumor

Tumor size

-

 

Tumor condition

Primary, recurrence; breast, axillary cavum

 

Size of resection

-

 

Type of resection

R0, R1, R2

 

Ulceration

Absent, present

 

Time of surgery

Up front; after neoadjuvant therapy (chemotherapy +/- radiotherapy)

 

Response to previous therapies

Stable disease; disease progression

 

Intention to treat

Curative, palliative

 

Metastasis

Absent; Oligometastatic; symptomatic

 

Histology

Histology; molecular subtype

Flap technique

Classical description; variation

-

 

Irrigation based

Thoracoabdominal or myocutaneous

 

Thoracoabdominal

Irrigation based/ random; lateral, medial

 

Myocutaneous

Type

 

Skin grafts

Absent; association with flaps

 

Size of the flap

-

 

Time of the surgical procedure

-

 

Hospitalization stay

-

 

Antibiotics

-

Complication

Absent or present

 

 

Infection

Primary, secondary to necrosis

 

Necrosis

Extension (tip, extensive)

 

 

Depth (epidermolysis, total skin necrosis)

 

Treatment of necrosis

Surgical revision, additional procedures: Expectant, local debridement, surgery with general anaesthesia

 

Dehiscence

-

 

Surgical healing time

Local control; beginning of the next adjuvant treatment

Patient

Patient

Age, BM, Smoking, Diabetes

 

Postoperative survival

Comorbidities; Mortality (chest wall resection)

 

Quality of life

-

 

Secondary breast reconstruction

-

Follow up

Local recurrence

-

 

Local free survival

-

 

Overall survival

-