Table 3: Comparisons of concentrations of biochemical parameters in patients with RTT who were less than or older than 8 years of age. Data are mean (SD).
|
Parameter |
Age < 8 years n=9 |
Age > 8 years n=6 |
P-value |
|
CSF-ACTH ng/ml |
33.6 (7.6) |
29.8 (6.2) |
0.56 |
|
CSF-glutamate nmol/l |
384 (132) |
320 (72) |
0.54 |
|
CSF-IGF-1 µg/l |
0.39 (0.18) |
0.56 (0.19) |
0.24 |
|
CSF-ACTH/glutamate-ratio |
0.11 (0.05) |
0.09 (0.03) |
1.0 |
|
CSF-IGF-1/glutamate-ratio |
0.0012 (0.0005) |
0.0017 (0.0008) |
0.31 |
|
CSF-Acetylcholinesterase activity nmol/mg prot/minute |
81.1 (30.7) |
73.2 (30.6) |
0.54 |
|
CSF-Nerve growth factor pg/ml |
3.24 (3.29) |
0.74 (1.27) |
0.31 |
CSF=cerebrospinal fluid, ACTH=adrenocorticotropic hormone, IGF= insulin-like growth factor