Table 3: Baseline cognitive tests compared to normal range [21, 22, 24].

 

 

Baseline

Normal range

Ivacaftor

MOCA score

27.6

>26

 

Trail A - speed seconds

28.06

22.93-39.32

Combination

MOCA score

27.48

>26

 

Trail A - speed seconds

25.40

22.93-31.78 (25)

 

Trail B - speed seconds

50.42

48.97-63.76 (25)

 

Cogstate™

 

 

 

ID - speed seconds

2.75

2.66-2.71 (28)

 

Maze – n errors

49.47

40.88-55.7 (28)

 

Shopping list - n correct

27.18

22.79-26.54 (28)

 

One back speed

2.91

2.79-2.9 (28)