Inclusion Criteria

1.              Alcoholic cirrhotics between 18-65 years of age (both inclusive) (diagnosed by clinical, biochemical, sonographic, radiological [CT scan] or histological evidence of cirrhosis and portal hypertension).

2.              Evidence of decompensated liver disease at screening (Child class B or C, Child-Pugh scores of ≥7 and <14).

3.              MELD scores of at least 10.

4.              Normal AFP Level (Normal AFP level to be considered as ≤ 40 ng/ml)

5.              Hb>10gm/dl.

6.              Female of childbearing potential should use double contraception, of which one should be a barrier method during the course of the study

7.              Signed informed consent.

Exclusion Criteria

1.              Patients listed for liver transplantation during screening

2.              Presence of advanced hepatic encephalopathy Grades 3 & 4 (West Haven criteria for grading of hepatic encephalopathy) at the time of screening.

3.              Active variceal bleed.

4.              Refractory ascites.

5.              Evidences of autoimmune liver disease: ANA (beyond 1:120 by immunoflourescence) or Anti-LKM positivity.

6.              Platelet count < 50,000/mm³.

7.              Serum Sodium <129mEq/L.

8.              Serum Creatinine > 1.2 mg/dl.

9.              Hepatocellular carcinoma or other malignancies

10.           Active infection in the body.

11.           Presence of severe underlying cardiac, pulmonary or renal disease.

12.           Excessive alcohol (>30 gm of alcohol/day) use in the last 3 months before screening.

13.           Positive HbSAg or antibodies to HIV or HCV.

14.           Pregnancy or lactation.

15.           Participation in any clinical trial within last 1 year

16.           Patients unable to consent

17.           Patients with hypersensitivity to the IMP and non-ionic radio contrast