Immunosuppressed Patients and the Risk of COVID-19: A Narrative Review

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Author Info

Fabrício Tavares Mendonça

Corresponding Author

Fabrício Tavares Mendonça
Department of Anesthesiology, Base Hospital of the Federal District, Brasilia, Federal District, Brazil

A B S T R A C T

Immunodeficiency is a disorder of the immune system characterized by the body's inability to establish effective immunity in response to various harmful agents, antigens. It results in an increased susceptibility to infections and can arise as a result of malnutrition, some types of cancer, infections such as HIV, iatrogeny or heredity. The newly discovered coronavirus is responsible for the current pandemic that is plaguing the world population. Most people with some type of immunodeficiency appear to be at greater risk of developing the severe form of the disease, due to its immunomodulatory effect in some patient populations. However, some immunomodulating agents have become the subject of discussion as possible treatments for the disease of the new coronavirus (COVID-19), increasing the importance of understanding its pathophysiological mechanisms and consequent control strategies. The main objective of this review is therefore to present the main global causes of immunodeficiency and their relationship with COVID-19.

Article Info

Article Type

Review Article

Publication history

Received: Fri 17, Jul 2020
Accepted: Fri 31, Jul 2020
Published: Tue 11, Aug 2020

Copyright

© 2023 Fabrício Tavares Mendonça . This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Hosting by Science Repository.
DOI: 10.31487/j.COR.2020.08.17