Co-Occurrence of Multiple Sclerosis & Ovarian Cancer: A Case Report and Literature Review

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Author Info

Fengxiang Han Caiwei Lu Chunxiang Luo Xiaohui Liao Donghua Xie Danni XU Yanda LU

Corresponding Author

Danni XU
Department of Oncology, The First Affiliated Hospital of Hainan Medical University, Haikou, Hainan, PR China

A B S T R A C T

Background: The possibility of an association between Multiple Sclerosis (MS) and cancer has not been thoroughly investigated. Case Presentation: We present a case of ovarian cancer in 58-year-old woman with MS. Radical hysterectomy, bilateral salpingo-oophorectomy, omentectomy, and pelvic and para-aortic lymph node dissection was performed. Pathohistological analysis and immunohistochemistry confirmed the diagnosis of a clear cell carcinoma of the left ovary, grade Ⅲ, FIGO2014 stage IA. Adjuvant chemotherapy of paclitaxel-carboplatin regimen (paclitaxel 175mg/m2, carboplatin AUC 6, at intervals of 3 weeks) was implemented for 4 courses. Conclusion: The occurrence of ovarian cancer in MS patients may be coincidental. Nevertheless, the longterm use of immunosuppressive and/or immunomodulatory drugs in MS and the incidence of cancer may be associated.

Article Info

Article Type

Case Report and Review of the Literature

Publication history

Received: Fri 11, Dec 2020
Accepted: Sat 02, Jan 2021
Published: Wed 27, Jan 2021

Copyright

© 2023 Danni XU. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Hosting by Science Repository.
DOI: 10.31487/j.GSCR.2020.02.14