An Almost Fatal Case of the Hypereosinophilic Syndrome: A Dilemma Between Vasculitis or Clonal Disorder

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Author Info

Aharon Kessel Alona Paz Anna Solopov Boaz Weller Doron Rimar Idit Dobrecky-Mery Ilana Levy Liliana Schliamser Milian Croitoru Nizar Jiries Shira Ginsberg Tamar Tadmor

Corresponding Author

Ilana Levy
Internal Medicine B Department, Bnai Zion Medical Center, Haifa, Israel

A B S T R A C T

Hypereosinophilic syndrome (HES) is a rare and potentially life-threatening disorder. While many conditions can cause eosinophilia, it can also be provoked by rarer diseases such as vasculitis or myeloproliferative disorders. Here we present an almost fatal presentation of HES characterized with both vasculitis and clonal features. Treatment with combined chemo-immunotherapy allowed reversal of most of the complications. There is still much uncertainty in the diagnosis and management of HES, and research should be done to improve knowledge on pathophysiology and cytogenetics of this disease in order to improve treatment and prevent life-threatening complications.

Article Info

Article Type

Case Report

Publication history

Received: Mon 25, Nov 2019
Accepted: Fri 20, Dec 2019
Published: Thu 26, Dec 2019

Copyright

© 2023 Ilana Levy. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Hosting by Science Repository.
DOI: 10.31487/j.JCMCR.2019.01.01