Sarcomatoid Carcinoma of the Urinary Bladder: A Case Report

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Author Info

Di Wu Haofan Jin Qiliang Yin Shijie Lan Yan Wang Yanping Zhong

Corresponding Author

Di Wu
Tumor Center of JiLin University No.1 Hospital, Changchun, China

A B S T R A C T

Introduction: Sarcomatoid carcinoma describes a biphasic malignancy with features of epithelial and mesenchymal differentiation. It rarely occurs at the urinary bladder but is usually aggressive and associated with poor prognosis. Case Presentation: We here report a case of sarcomatoid carcinoma of the urinary bladder of a 48 years old man with intermittent painless haematuria over an 18-month period. Imaging examination showed intraluminal protrusion of a tumour on the right posterior wall of the bladder. Diagnosis: The patient was initially diagnosed as a right bladder mass. Interventions: The patient underwent two rounds of transurethral resection of bladder tumour (TURBT) and pathological analysis suggested the tumours were invasive urothelial carcinomas. Radical cystectomy was later performed, and pathological analysis suggested a stage T4 sarcomatoid carcinoma. The patient received 5 cycles of gemcitabine and cisplatin. Outcome: The patient died of multiple organ dysfunction syndrome 8.5 months after the diagnosis of sarcomatoid carcinoma. Conclusion: Sarcomatoid carcinoma of the urinary bladder is a highly malignant disease, and the histopathological characteristics are distinct. The diagnosis, surgical management, and chemotherapy of this patient are discussed together with previous cases reported in the literature

Article Info

Article Type

Case Report

Publication history

Received: Fri 27, Mar 2020
Accepted: Wed 15, Apr 2020
Published: Fri 08, May 2020

Copyright

© 2023 Di Wu. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Hosting by Science Repository.
DOI: 10.31487/j.JSO.2020.02.05