Prophylactic Urethrectomy Could Further Shorten the Female Bladder Cancer Recurrence and Metastasis

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Author Info

Quanxin Su Shenglin Gao Jiasheng Chen Lifeng Zhang Li Zuo

Corresponding Author

Lifeng Zhang
Department of Urology, The Affliated Changzhou No. 2 People’s Hospital of Nanjing Medical University, Changzhou, Jiangsu, China

A B S T R A C T

Objective: To compare the clinical effects and safety of two methods of laparoscopic total cystectomy for female bladder cancer patients with retention and resection of the urethra. Methods: Female bladder cancer patients with bladder invasive urothelial carcinoma were selected in grade II~III from January 2008 to March 2018. Patients were divided into two groups based on the surgical method: group A laparoscopic radical cystectomy, and group B laparoscopic radical cystectomy + urethrectomy, to observe the clinical efficacy, operation duration, blood loss during surgery, hospitalization time, and complications. Results: The operation times in groups A and B were 262.54 ± 27.95 min and 310.28 ± 32.99 min, respectively. The volumes of intraoperative blood loss in groups A and B were 439.46 ± 44.52 mL and 456.74 ± 47.18 mL, respectively. There were no discernable differences in the probability of postoperative complications in the two groups. In group A, four patients experienced bladder cancer recurrence and metastasis, and 50% of these cases had a urethral recurrence. In group B, one patient experienced bladder cancer recurrence and metastasis; however, there was no urethral recurrence. Conclusion: Although laparoscopic radical cystectomy + urethrectomy extended the operation times; prophylactic urethrectomy can further shorten the bladder cancer recurrence and metastasis and improve patient prognosis without an increase in complications. However, its long-term clinical efficacy needs further study and supplement.

Article Info

Article Type

Research Article

Publication history

Received: Tue 21, Jul 2020
Accepted: Tue 04, Aug 2020
Published: Fri 14, Aug 2020

Copyright

© 2023 Lifeng Zhang. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Hosting by Science Repository.
DOI: 10.31487/j.JSO.2020.04.07