Thrombolytic Treatment in High-Risk Pregnancy: A Case Report

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Author Info

Enzo Sanzaro

Corresponding Author

Enzo Sanzaro
Department of Neurology and Stroke Unit of Umberto I Hospital, Siracusa, Italy

A B S T R A C T

Ischemic stroke during pregnancy occurs most often in the third trimester and is potentiated by an increased pro-coagulant state during pregnancy. Precisely this procoagulant state, associated with other thrombophilic phenomena and various risk factors for cardio- and cerebro-vascular pathologies, is the basis of a stroke in the elderly pregnant woman. A 43-year-old woman of 30 weeks pregnant presented within 120 minutes of the sudden onset of left side hemiparesis was given thrombolytic treatment with recombinant tissue plasminogen activator. The risk was extremely high since in the past she had a premature birth for unknown reasons. Our patient improved clinically with no residual deficits. But, being at risk, she was transferred to another hospital where she spontaneously gave birth, after a few days, to a healthy premature baby. It is reasonable to weigh in the benefit of alteplase vs. the risk in this patient group and give treatment for disabling stroke, particularly if there is no access to endovascular treatment.

Article Info

Article Type

Case Report

Publication history

Received: Tue 14, Apr 2020
Accepted: Tue 12, May 2020
Published: Fri 15, May 2020

Copyright

© 2023 Enzo Sanzaro. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Hosting by Science Repository.
DOI: 10.31487/j.NNB.2020.02.06