Most Appropriate Radiation Therapy Techniques for The Breast Cancer Treatment: Dosimetric Analysis of Three Different Radiation Therapy Methods

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Author Info

Salim Nidal Kristina Tumanova Alexey Popodko Alexander Stolbovoy

Corresponding Author

Kristina Tumanova
Department of Radiation Oncology, European Medical Center, Moscow, Russia

A B S T R A C T

Background: Radiation-induced cardiac events and pneumonitis are the major late radiotherapy side effects. Methods: We explored the differences in dose distribution between 3D CRT, IMRT and VMAT in 125 women with unilateral breast cancer. The various dose distribution to the tumor and OARs were studied for left and right sided irradiation. Results: Upon using 3D CRT breasts with lymph nodes, we observed a significant dose increase in the ipsilateral lung. Having irradiated only the right breast, there was a negligible Dmean difference to the adjacent lung between three methods, likewise for the myocardium in left breast cases. For right-sided cases 3D CRT showed the lowest doses in myocardium. Conclusion: Radiation oncologists should consider VMAT if conditions do not allow devising three plans with different methods. This in turn will reduce cardio and pneumotoxicity of left breast cancer treatment. In the treatment of right breast cancer, physicians should focus on 3D CRT.

Article Info

Article Type

Research Article

Publication history

Received: Mon 15, May 2023
Accepted: Wed 31, May 2023
Published: Mon 19, Jun 2023

Copyright

© 2023 Kristina Tumanova. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Hosting by Science Repository.
DOI: 10.31487/j.RCO.2023.01.01