article = {AJSCR-2021-1-104} title = {Primary Localised Amyloidosis of the Urethra: A Case Report} journal = {American Journal of Surgical Case Reports} year = {2021} issn = {2674-5046} doi = {http://dx.doi.org/10.31487/j.AJSCR.2021.01.04} url = {https://www.sciencerepository.org/primary-localised-amyloidosis-of-the-urethra_AJSCR-2021-1-104 author = {Nawal Khan,Kamran Ahmed,Catherine Horsfield,Sachin Malde,Majed Shabbir,} keywords = {Amyloidosis, urethral stricture, haematuria} abstract ={Primary localised amyloidosis of the urethra is a rare entity with only 50 cases reported in the literature. The deposition of fibrillary proteins can lead to a range of symptoms. Importantly, the clinical and cystoscopic features may mimic urethral malignancy (haematuria, voiding difficulties, and a palpable urethral mass), and so thorough investigation is required in order to exclude malignancy, and to identify features of generalised amyloidosis which has a poor prognosis. Once diagnosed the prognosis of localised amyloidosis is excellent, although disease recurrence is possible. We describe a case of primary localised urethral amyloidosis presenting with visible haematuria and a urethral stricture and reviewed the literature regarding management of this rare condition.}