article = {COR-2018-1-113}
title = {Spontaneous splenic rupture in polycythemia vera}
journal = {Clinical Oncology and Research}
year = {2018}
issn = {2613-4942}
doi = {http://dx.doi.org/10.31487/j.COR.2018.10.013}
url = {https://www.sciencerepository.org/spontaneous-splenic-rupture-in-polycythemia-vera_COR-1-113 
author = {Christine  Moore,Donald R  Fleming,Mailien R  Rogers,}
keywords = {Hematology, polycythemia vera, splenic rupture, splenomegaly, thrombocytosis, case report}
abstract ={Atraumatic spontaneous splenic rupture is rare and occurs in the setting of spleen pathology from a myriad
of causes, including myeloproliferative disorders. Only four previously reported cases of atraumatic
spontaneous splenic rupture associated with polycythemia vera exist. We report the fifth case, which also is
the first with severe thrombocytosis requiring multiple plateletpheresis despite medical therapy and
excellent long-term control. In addition to reporting the fifth case of spontaneous splenic rupture in a
polycythemia vera patient, we also review the risks associated with splenectomy in patients with
polycythemia vera and therapies that can prevent spontaneous splenic rupture.}