article = {COR-2020-1-110} title = {Primary Retroperitoneal Serous Cystadenoma Mimicking Rectal Duplication Cyst: A Case Report} journal = {Clinical Oncology and Research} year = {2020} issn = {2613-4942} doi = {http://dx.doi.org/10.31487/j.COR.2020.01.10} url = {https://www.sciencerepository.org/primary-retroperitoneal-serous-cystadenoma-mimicking-rectal_COR-2020-1-110 author = {Hunter Jecius,Mary Junak,Mohammad Hamidi,Valentine Nfonsam,} keywords = {Serous cystadenoma, retroperitoneal, rectal duplication cyst, incontinence} abstract ={Background: Primary retroperitoneal serous cystadenomas (PRSCs) are extremely rare, and their pathogenesis is not well understood. Differentiating these tumors from other cystic or tumorigenic lesions can be challenging given the unusual retroperitoneal location and varied symptomatology. Case Presentation: An 83-year-old female was evaluated for vaginal prolapse symptoms, fecal incontinence, and intermittent mixed urinary incontinence symptoms. Magnetic resonance imaging showed a large space-occupying cystic structure closely associated with the rectum. After exploratory laparotomy with excision of the retroperitoneal mass, biopsy showed a simple cyst filled with serous fluid and lined by a single layer of cuboidal epithelial cells consistent with serous cystadenoma. On follow up visit, she reported improvement in stress urinary incontinence, but continued to have difficulty with urinary and bowel urge incontinence. Conclusion: PRSCs should be considered during evaluation of retroperitoneal space-occupying lesions despite the rarity of serous cystadenomas being found in this location. The pathophysiology of how PRSCs arise is still not well understood but establishing better techniques to distinguish these lesions from other cystic and tumorigenic lesions should be investigated.}