article = {COR-2020-4-107}
title = {Synthesis, Characterization and Cytotoxic Studies of Benzamide Derivatives of Anacardic Acid using Human Liver Cancer Cells}
journal = {Clinical Oncology and Research}
year = {2020}
issn = {2613-4942}
doi = {http://dx.doi.org/10.31487/j.COR.2020.04.07}
url = {https://www.sciencerepository.org/synthesis-characterization-and-cytotoxic-studies-of-benzamide-derivatives_COR-2020-4-107 
author = {Basappa .,Dinesh  Rangappa,K.N.  Thanuja,Kanchugarakoppal S.  Rangappa,M. Navya  Rani,Toreshetahally R.  Swaroop,}
keywords = {Anacardic acid, cytotoxic, HepG2, benzamid}
abstract ={Naturally occurring anacardic acid based benzamides were reported to show anti-inflammatory and
anticancer activities, where we synthesized and characterized by NMR and HRMS analysis and also tested
a series of anacardic acid based benzamides and evaluated against the proliferation of human liver cancer
cells (HepG2). Among the tested compounds, 6j-m showed good inhibitory activity against HepG2 cells
with IC50 values ranging from 78.2-91.9 μM. In conclusion, we herein reported the newer series of an
academic acid benzamides for the first time.}