article = {COR-2020-6-106} title = {Pulmonary Mucosa-Associated Lymphoid Tissue Lymphoma- A Single Center Review of the Diagnostic Approach} journal = {Clinical Oncology and Research} year = {2020} issn = {2613-4942} doi = {http://dx.doi.org/10.31487/j.COR.2020.06.06} url = {https://www.sciencerepository.org/pulmonary-mucosa-associated-lymphoid-tissue-lymphoma-a-single-center-review_COR-2020-6-106 author = {Aisling Farrell,Farrell SA,Henry MT,Kennedy MP,} keywords = {Lung cancer, bronchoalveolar lavage, cryobiopsy, MALT, transbronchial biopsy} abstract ={Pulmonary mucosa-associated lymphoid tissue (MALT) lymphoma is a rare disease, and diagnosis is difficult, often requiring multiple attempts at tissue sampling. The aim of this review was to evaluate the diagnostic pathway. A retrospective review was performed of patients diagnosed with pulmonary MALT lymphoma in a tertiary referral lung cancer center over 9 years. Ten patients were identified, and each diagnostic and treatment approach was analysed. 30% were diagnosed via transbronchial biopsy, two with the assistance of radial probe ultrasound guidance and one with transbronchial lung cryobiopsy of a predetermined CT-guided targeted segment. 70% were diagnosed following surgical biopsy. 40% had localized disease. The diagnosis was not successfully achieved until a large-sized tissue specimen was obtained. The implementation of novel bronchoscopy techniques can assist in reducing the number of invasive surgical procedures required to obtain a diagnosis. All cases should be discussed in a multidisciplinary setting prior to diagnostic attempts. }