article = {COR-2020-6-108}
title = {Evidence for Edible Chinese Herbal Medicine as an Alternative Approach for the Treatment of Colorectal Cancer}
journal = {Clinical Oncology and Research}
year = {2020}
issn = {2613-4942}
doi = {http://dx.doi.org/10.31487/j.COR.2020.06.08}
url = {https://www.sciencerepository.org/evidence-for-edible-chinese-herbal-medicine-as-an-alternative-approach_COR-2020-6-108 
author = {Calvin  Kai-Fai Lee,George  Pak-Heng Leung,Hai-Yong  Chen,Hei  Wan,Jing  Su,Kalin Yan-Bo ZHANG,Kar-Ho  Lam,Ling-Min  Tian,Min-Yi  Tian,Sonny  Hing-Min Tse,Sydney  Chi-Wai Tang,Wei  Meng,Xiang  Lin,Xiao-Xin  Chen,Yi-Bin  Feng,Zhang-Jin  Zhang,}
keywords = {Chinese herbal medicine, colorectal cancer, functional food, diet therapy}
abstract ={Colorectal cancer (CRC) is the leading cause of cancer lethality worldwide, inflicting a heavy burden on
society. Unfortunately, the complex nature of CRC pathogenesis renders current chemotherapies and
targeted therapies unsatisfactory. Conventional medicine generally concentrates on the killing of tumor cells
by inducing cell death or activation of the immune system, which often leads to adverse effects or relapsed
chemoresistance. On the contrary, Chinese medicine theory pays attention to the patients’ whole inner
system and helps to shrink the tumor with consideration of overall body condition. Since numerous Chinese
herbal medicines (CHM) are used as food, the edible CHMs as diet resources therapy represent a promising
alternative for the treatment of CRC. Recent research has made remarkable progress toward the therapeutic
effects of edible CHM for CRC. In this review, experimental CRC models, the holistic characteristic of
edible CHM, and recent research on the efficacy and mechanisms of edible CHM as anti-CRC agents are
discussed, as well as the safety aspect of edible CHM.}