article = {JBEM-2019-1-104} title = {Synthesis and Antimicrobial Activities of Containing Sulfur Heterocyclic Curcumin Derivatives} journal = {Journal of Biology Engineering and Medicine} year = {2019} issn = {} doi = {http://dx.doi.org/10.31487/j.JBEM.2019.01.04} url = {https://www.sciencerepository.org/synthesis-and-antimicrobial-activities-of-containing-sulfur-heterocyclic_JBEM-2019-1-104 author = {Dan Wang,Dunjia Wang,Heng Lyu,Hengyi Du,Lian Cai,} keywords = {Curcumins, sulfur heterocycle, synthesis, antimicrobial activity} abstract ={Eight novel containing sulfur heterocyclic curcumins were synthesized and characterized by 1H-NMR, FTIR and MS spectroscopy. Their antimicrobial activities against Staphylococcus aureus, Bacillus subtilis, Escherichia coli and Aspergillus niger were also tested for MIC by using serial tube dilution method. The results showed that the antimicrobial activities of synthesized curcumin derivatives were better than curcumin. Especially, the compound 4-(1,3-dithiolan-2-ylidene)-1,7-di(thiophen-2-yl) hepta-1,6-diene-3,5- dione (2g) exhibited excellent the antimicrobial activities among these curcumin derivatives.}