article = {JSO-2019-2-104}
title = {Is there any differences in post-operative course among the three main types of periampullary tumour?}
journal = {Journal of Surgical Oncology}
year = {2019}
issn = {2674-3000}
doi = {http://dx.doi.org/10.31487/j.JSO.2019.02.04}
url = {https://www.sciencerepository.org/is-there-any-differences-in-post-operative-course-among-the-three-main-types-of-periampullary-tumour_JSO-2019-2-104 
author = {Ho- Seong ,Jai Young  Cho,Mohamed Rabie  Saad,Yoo-Seok  Yoon,}
keywords = {Post-operative complication, pancreatic head cance, distal CBD cancer, ampulla of vater cancer, post-operative course of periampullary tumour}
abstract ={Background and objectives: There have been many reports of pancreaticoduodenectomy performed for
the surgical treatment of periampullary cancer. However, any differences in the perioperative courses of
different types of periampullary tumour are unclear. In this study, we evaluated the differences in morbidity
among the three main types of periampullary tumour.
Methods: Prospectively collected data from patients who underwent pancreaticoduodenectomy for
periampullary tumour between 2004 to 2018 were reviewed. The patients were divided into three groups:
those with pancreatic head cancer, ampulla of Vater (AOV) cancer, or distal common bile duct (CBD)
cancer.
Results: Among the 645 patients who underwent pancreaticoduodenectomy, 298 (46.2%) were diagnosed
with pancreatic head cancer, 172 (26.7%) with AOV cancer, and 175 (27.1%) with distal CBD cancer. The
group with distal CBD cancer had the highest mean age (68.45 ± 9.2 years; p = 0.002) and the highest total
bilirubin level (8.72 ± 0.6) mg/dl among the three groups. The group with pancreatic head cancer had the
highest rate of firm pancreatic texture (71.7%) and the greatest duct diameter (4.64 ± 0.2 mm) among the
three groups. Pancreatic fistula and pulmonary complications were more frequent in the groups with AOV
cancer and distal CBD cancer. Post-operative haemorrhage occurred at a higher rate in the group with distal
CBD cancer (12%). The hospital stay was longer in the group with distal CBD cancer (27.30 ± 1.3 days).
Conclusion: Among the three main types of periampullary tumour, the group with distal CBD cancer had
the highest complication rate and the longest hospital stay.}