article = {JSO-2020-5-103}
title = {Microbiome in GIT Cancers: New Frontiers in Personalized Medicine – A Review of Literature}
journal = {Journal of Surgical Oncology}
year = {2020}
issn = {2674-3000}
doi = {http://dx.doi.org/10.31487/j.JSO.2020.05.03}
url = {https://www.sciencerepository.org/microbiome-in-git-cancers-new-frontiers-in-personalized-medicine_JSO-2020-5-103 
author = {Maha Saad,Mansour Mohamed Kabash,Aymn El Sayed Shafei,Rawan Ellackany,Ahmed Atef,Mostafa Wael,Marwa Matboli,}
keywords = {Gut microbiome, gastrointestinal tract, cancer, therapy, molecular pathogenesis}
abstract ={Every person has a characteristic “enterotype,” the gut components and the environment. Recently, a strong
biological correlation has emerged among the microbiome of the gut, the immune system, cancer
development and pharmacological effects of chemotherapy. In this review, we outline the role of gut
microbiota in the gastrointestinal tract (GIT) cancers pathogenesis and their implications for enhancing the
efficacy of GIT cancer management in clinical practice. We also summarize the molecular pathways linking
gut microbiota and GIT cancers and the effectiveness of manipulating microbiota in GIT cancer therapies
such as personalized cancer therapy.
}