article = {PDR-2020-2-104}
title = {Depressive Disorders and Incidence of COVID-19: Is There a Correlation and Management Interference?}
journal = {Psychological Disorders and Research}
year = {2020}
issn = {2674-2470}
doi = {http://dx.doi.org/10.31487/j.PDR.2020.02.04}
url = {https://www.sciencerepository.org/depressive-disorders-and-incidence-of-covid-19-is-there-a-correlation_PDR-2020-2-104 
author = {Nagwa  Ali Sabri,Mohamed  Ahmed Raslan,Eslam  Mansour Shehata,Sara  Ahmed Raslan,}
keywords = {COVID-19, depression, SSRIs, antidepressants, direct acting antivirals}
abstract ={Corona virus Disease-2019 is a new strain of Coronaviruses (COVID-19) causing an infection which has
rapidly spread all over the Globe, where the primary pathways of infection spreading reported to be through
large respiratory droplets and the disease severity has varied from mild self-limiting flu like illness to acute
pneumonia, respiratory collapse and death. On the other hand, depression is a disease that could be progress
to a life-threatening condition that affects globally hundreds of millions of people. The aim of this review
is desired to investigate and find a correlation between depressive disorders and the incidence of COVID19, where, pathogeneses of depressive disorder and its effect on the immunity system was addressed, besides
the impact of depression on individual food intake and its complications regarding weight gain, insulin
resistance, and immune system disruption was also discussed which by turn might increase the risk for
infection with COVID-19. Finally, the possible drug-drug interactions between drugs included in
management protocols of both depressive disorder including antidepressants and anxiolytics and COVID19 with possible proposed alternatives.}