article = {RDI-2019-3-104} title = {Sono and photo stimulated Chlorine E6 nanocomposite in tumor-bearing mice: upcoming cancer treatment} journal = {Radiology and Medical Diagnostic Imaging} year = {2019} issn = {2613-7836} doi = {http://dx.doi.org/10.31487/j.RDI.2019.03.04} url = {https://www.sciencerepository.org/sono-and-photo-stimulated-chlorine-e6-nanocomposite-in-tumor-bearing-mice-upcoming-cancer-treatment_RDI-2019-3-104 author = {Ammar Yahya Kadhim Almamoori,Gihan Hosny Abd Elsamie,Metwally Aly Metwally,Samir Ali ,} keywords = {Nano-Chlorine E6, ehrlich tumor, sonodynamic therapy, photodynamic therapy} abstract ={This study was directed at study the effectiveness of cancer targeted therapy using the activated Chlorine E6 nanocomposite (Nano-CE6). Study was applied on male Swiss albino mice, implanted with Ehrlich tumor (EAC) divided into six groups. Two energy sources were used; laser and Ultrasound. Results showed that Nano-CE6 is a potential sensitizer for photodynamic or sonodynamic treatment of tumor. NanoCE6 plays an important role in tumor growth inhibition and cell death induction. Activated Nano-CE6 with both infrared laser and ultrasound has a potential antitumor effect. The results indicated that (FA–NGO– CE6) could be used as a unique nanocomposite for cancer targeted therapy SPDT. }