article = {SCR-2021-1-119} title = {Complications and Cure Rates of Parathyroidectomy for Primary Hyperparathyroidism with Negative Localization Studies} journal = {Surgical Case Reports} year = {2021} issn = {2613-5965} doi = {http://dx.doi.org/10.31487/j.SCR.2021.01.19} url = {https://www.sciencerepository.org/complications-and-cure-rates-of-parathyroidectomy-for-primary-hyperparathyroidism_SCR-2021-1-119 author = {Bassam Abboud,Georges Assaf,Fares Yared,Alaa El-Kheir,} keywords = {Primary hyperparathyroidism, MIBI scan, ultrasound, adenoma, multiple lesions} abstract ={Purpose: This paper evaluates the outcomes of parathyroidectomy for primary hyperparathyroidism with negative localization studies. Methods: All patients with primary hyperparathyroidism with negative preoperative ultrasound and MIBI scan who underwent parathyroidectomy were retrospectively included. Three groups were defined. Group 1 included the patients with negative ultrasound and MIBI. Group 2 included the patients with negative ultrasound and positive MIBI. Group 3 included the patients with positive ultrasound and negative MIBI. Results: In Group 1, 51% and 86% of patients had one adenoma and atypical localizations respectively. Unique adenoma and atypical localizations were showed in 87% and 93% of patients in Group 2 respectively. In Group 3, 83% and 17% of patients had one adenoma and atypical localizations respectively. No cervical hematoma was noted. Transient recurrent laryngeal nerve palsy occurred in 2 patients. Seven patients required postoperative calcium supplementation for 2 to 5 months, and one had recurrent hypercalcemia at follow-up. Cure rate was 98,3%. Conclusion: When US and MIBI were negative, multiple lesions and atypical localizations were frequent. The success rate and postoperative complications were not affected with this event.}