TY - JOUR
AR - AJSCR-2020-3-109
TI - Investigating the Role of Open Lung Biopsy in Diagnosing the Type of Chronic Lung Disease in Children
AU - Ashjaei, Bahar
AU - Modaresi , Mohammadreza
AU - Amiri , Shakiba
AU - Najdi , Fatemeh
AU - Movahedi , Jadid Merisa
AU - Aghabarari , Mojtaba
AU - Ghavami , Adel Maryam
JO - American Journal of Surgical Case Reports
PY - 2020
DA - Mon 17, Aug 2020
SN - 2674-5046
DO - http://dx.doi.org/10.31487/j.AJSCR.2020.03.09
UR - https://www.sciencerepository.org/investigating-the-role-of-open-lung-biopsy-in-diagnosing-the_AJSCR-2020-3-109 
KW - Chronic pulmonary disease, lung biopsy, pulmonary disease diagnosis, children
AB - Objective: This study was conducted for the practical use of biopsy in the diagnosis of chronic lung disease
and the guidance of risks and benefits.
Design of Study: We studied 64 children with chronic lung disease who underwent open lung biopsy in 5
years at the Children's Medical Center .
Results: Biopsy results were diagnostic in 57 cases (89.1%) and non-diagnostic in 7 cases (10.9%). The
biopsy determined the type of mass in all cases where a possible diagnosis of lung mass or thoracic wall
was made. In 37 cases (57.8%) the diagnosis was changed and the exact diagnosis was determined. The
main side effects (including pneumothorax, hemothorax, pyothorax, and pleural effusion) were 50% (32
cases), the most common of which were pneumothorax and pleural effusion, with a total of more than 87%
of these major complications. 22 patients (34.4%) required intubation. 24 patients (37.5%) were admitted
to the ICU after surgery. The death occurred in only one case, who was a 3-month-old boy with a disorder
of INR and suffering from acute respiratory distress syndrome. There was no mortality that could be directly
related to surgery.
Conclusion: Open lung biopsy is a gold standard for the histological diagnosis of chronic pulmonary disease
in children and plays an important role in the treatment of children with chronic pulmonary diseases.
However, serious and common side effects of this method should be considered