TY - JOUR
AR - AJSCR-2021-1-104
TI - Primary Localised Amyloidosis of the Urethra: A Case Report
AU - Nawal, Khan
AU - Kamran, Ahmed
AU - Catherine, Horsfield
AU - Sachin, Malde
AU - Majed, Shabbir
JO - American Journal of Surgical Case Reports
PY - 2021
DA - Fri 03, Sep 2021
SN - 2674-5046
DO - http://dx.doi.org/10.31487/j.AJSCR.2021.01.04
UR - https://www.sciencerepository.org/primary-localised-amyloidosis-of-the-urethra_AJSCR-2021-1-104 
KW - Amyloidosis, urethral stricture, haematuria
AB - Primary localised amyloidosis of the urethra is a rare entity with only 50 cases reported in the literature. The 
deposition of fibrillary proteins can lead to a range of symptoms. Importantly, the clinical and cystoscopic 
features may mimic urethral malignancy (haematuria, voiding difficulties, and a palpable urethral mass), 
and so thorough investigation is required in order to exclude malignancy, and to identify features of 
generalised amyloidosis which has a poor prognosis. Once diagnosed the prognosis of localised amyloidosis 
is excellent, although disease recurrence is possible. We describe a case of primary localised urethral 
amyloidosis presenting with visible haematuria and a urethral stricture and reviewed the literature regarding 
management of this rare condition.