TY - JOUR
AR - CEI-2020-1-106
TI - Association of Test Results for 33 Frequently Used Laboratory Tests with Body Mass Index (BMI)
AU - Anders, Larsson
AU - Johan, Ärnlöv
AU - Johanna, Helmersson-Karlqvist
AU - Lars Lind, 
AU - Peter Ridefelt, 
JO - Clinical and Experimental Investigations
PY - 2020
DA - Tue 28, Jan 2020
SN - 2674-5054
DO - http://dx.doi.org/10.31487/j.CEI.2020.01.06
UR - https://www.sciencerepository.org/association-of-test-results-for-33-frequently-used_CEI-2020-1-106 
KW - 80-year-old population, BMI, alanine aminotransaminase, CRP, cystatin C
AB - Once considered a problem only for high-income countries, obesity rates are now rising worldwide. When
evaluating test results from obese patients it is important to be aware of the effect of obesity on individual
laboratory test results. The aim of the present study was to study the association between body mass index
(BMI) and a group of frequently requested laboratory tests to evaluate which of these analytes that are
affected by BMI. We analyzed the association between body mass index (BMI) and Alanine
aminotransaminase (ALT), Albumin, Alkaline phosphatase, Pancreatic amylase, Apolipoprotein A1,
Apolipoprotein B, Apolipoprotein B/Apolipoprotein A1 ratio, Aspartate aminotransferase (AST),
AST/ALT ratio, Bilirubin, Calcium, Calprotectin, Cholesterol, HDL-cholesterol, Creatinine kinase (CK),
Creatinine, C-reactive protein, Cystatin C, Gamma-glutamyl transferase (GGT), Iron, Iron saturation,
Lactate dehydrogenase (LDH), Magnesium, Phosphate, Transferrin, Triglycerides, Urate, Urea, Zink,
Hemoglobin, Platelet count and White blood cell count in an 80-year old population (n=531, 266 females
and 265 males). There were significant Spearman rank associations between BMI and laboratory test results
for several of the studied markers in both females and males. The strongest associations with BMI were
noted for ALT, Apolipoprotein A1, HDL-cholesterol, Hemoglobin, CRP, Cystatin C, Triglycerides and
Urate. In conclusion, several of the most frequently used laboratory markers are significantly associated
with BMI. To be able to correctly interpret a test result it is important to be aware of the effects of BMI on
the test results.