TY - JOUR
AR - COR-2020-3-113
TI - A Unique Case of Chronic Myeloid Leukemia Occurring in an Adolescent Male
AU - Dawood, Findakly
AU - Mohammed Al-Charakh, 
AU - Surabhi Amar, 
JO - Clinical Oncology and Research
PY - 2020
DA - Tue 31, Mar 2020
SN - 2613-4942
DO - http://dx.doi.org/10.31487/j.COR.2020.03.13
UR - https://www.sciencerepository.org/a-unique-case-of-chronic-myeloid_COR-2020-3-113 
KW - Chronic myeloid leukemia, adolescents and young adultstyrosine, kinase inhibitor 
AB - Background: Patients with chronic myeloid leukemia (CML) usually present in elderly age and rarely in
the adolescents and young adults (AYA) population. There is a limited understanding of disease
management and survival outcomes in this group of patients.
Case Presentation: An 18-year-old man presents to our hospital for abdominal pain and weight loss.
Examination pertinent for splenomegaly and labs significant for profoundly elevated white cells count. FISH
was positive for BCR/ABL1 fusion gene, and thus, he was diagnosed with CML and treated with TKI with
clinical improvement.
Conclusion: Tailoring CML novel therapeutic strategies in the AYA population to different disease
characteristics will better advance our understanding of this disease in this patient population.