TY - JOUR
AR - COR-2020-7-107
TI - Primary Cutaneous Diffuse Large B-Cell Lymphoma, Leg Type: A Narrative Review
AU - Nathaniel A., Parker
AU - Ammar , Al-Obaidi
AU - Al Hadeethi , D
AU - Choucair , K
AU - Truong , PV
JO - Clinical Oncology and Research
PY - 2020
DA - Mon 20, Jul 2020
SN - 2613-4942
DO - http://dx.doi.org/10.31487/j.COR.2020.07.07
UR - https://www.sciencerepository.org/primary-cutaneous-diffuse-large-b-cell-lymphoma-leg-type_COR-2020-7-107 
KW - Primary cutaneous lymphoma, primary cutaneous b-cell lymphoma, primary cutaneous diffuse large b-cell lymphoma, leg type, primary cutaneous follicle center lymphoma, primary cutaneous marginal zone lymphoma
AB - Primary cutaneous lymphomas are rare manifestations of extranodal lymphomas. Comprising the majority
of cutaneous lymphoma cases with neoplastic B-cell origins, three main subtypes exist. In general, grossly
and microscopically these subtypes are similar. However, these are three distinct variants with diverse
clinicopathologic, cytogenetic, molecular, and prognostic features. Primary cutaneous diffuse large B-cell
lymphoma, leg type is an exceedingly rare and aggressive variant of primary cutaneous B-cell lymphomas.
Thus, increased clinical awareness is needed to differentiate between the three subtypes because earlier
identification not only leads to the appropriate treatment, but also improved survival. Here, characteristic
features of the three predominant variants of primary cutaneous B-cell lymphomas are presented while
remaining focused on the most aggressive subtype- primary cutaneous diffuse large B-cell lymphoma, leg
type.