TY - JOUR
AR - COR-2020-8-117
TI - Immunosuppressed Patients and the Risk of COVID-19: A Narrative Review
AU - Fabrício Tavares , Mendonça 
JO - Clinical Oncology and Research
PY - 2020
DA - Tue 11, Aug 2020
SN - 2613-4942
DO - http://dx.doi.org/10.31487/j.COR.2020.08.17
UR - https://www.sciencerepository.org/immunosuppressed-patients-and-the-risk-of-covid-19-a-narrative-review_COR-2020-8-117 
KW - Immunosuppression, immunosuppressants, infection, coronavirus, COVID-19
AB - Immunodeficiency is a disorder of the immune system characterized by the body's inability to establish
effective immunity in response to various harmful agents, antigens. It results in an increased susceptibility
to infections and can arise as a result of malnutrition, some types of cancer, infections such as HIV, iatrogeny
or heredity. The newly discovered coronavirus is responsible for the current pandemic that is plaguing the
world population. Most people with some type of immunodeficiency appear to be at greater risk of
developing the severe form of the disease, due to its immunomodulatory effect in some patient populations.
However, some immunomodulating agents have become the subject of discussion as possible treatments for
the disease of the new coronavirus (COVID-19), increasing the importance of understanding its
pathophysiological mechanisms and consequent control strategies. The main objective of this review is
therefore to present the main global causes of immunodeficiency and their relationship with COVID-19.